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It is the **IHC test** that is usually done first, and the doctor will look at the HER2 protein levels in the cancer cells. If the IHC test is negative, the cancer is considered HER2-negative. If the IHC test is positive, or if the result is unclear, it might be necessary to do a **FISH test**. A FISH test examines the HER2 gene and is more precise. The doctor will look at the results of the HER2 tests, and will use them to develop a treatment plan.
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